ACYLATION Meaning and
Definition
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Acylation is a chemical reaction that involves the introduction of an acyl group into a compound. An acyl group is a functional group derived from an acid, typically an organic acid, by removing the hydroxyl group. The acyl group is represented by the general formula RCO-, where R is an alkyl or aryl group. Acylation reactions play a fundamental role in various chemical processes, particularly in organic synthesis.
In acylation reactions, the acyl group is transferred from an acylating agent to another molecule, resulting in the formation of a new compound known as an acyl derivative. This transfer typically occurs through the formation of a covalent bond between the acyl group and the nucleophilic site on the target molecule. The nucleophilic site may be a heteroatom, such as oxygen or nitrogen, or a carbon atom capable of donating an electron pair.
Acylation reactions are widely utilized in the preparation of pharmaceuticals, agrochemicals, and specialty chemicals, as they can introduce specific functionality and alter the reactivity of the target molecule. Common examples of acylation reactions include the Friedel-Crafts acylation, which is used to synthesize aromatic ketones, and the acylation of amines, which yields amides. Furthermore, acylation can occur in biological systems as a step in various metabolic pathways, such as the acylation of cholesterol in the formation of steroidal hormones.
Overall, acylation plays a crucial role in both synthetic chemistry and biochemistry, enabling the modification and functionalization of organic molecules for a wide range of applications.
Common Misspellings for ACYLATION
- zcylation
- scylation
- wcylation
- qcylation
- axylation
- avylation
- afylation
- adylation
- actlation
- acglation
- achlation
- aculation
- ac7lation
- ac6lation
- acykation
- acypation
- acyoation
- acylztion
- acylstion
Etymology of ACYLATION
The word "acylation" is derived from the combination of the prefix "acyl-" and the suffix "-ation". The prefix "acyl-" comes from the organic functional group "acyl", which is derived from the carboxylic acid group (-COOH). The suffix "-ation" is a noun-forming suffix used to indicate an action, process, or result. Therefore, "acylation" refers to the process or action of introducing an acyl group into a molecule.
Similar spelling word for ACYLATION
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