COLISTIN SULFOMETHATE Meaning and
Definition
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Colistin Sulfomethate is an antimicrobial drug that belongs to a class called polymyxins. It is a combination of colistin and sulfomethate, and is primarily used to treat infections caused by multidrug-resistant Gram-negative bacteria, especially those resistant to other commonly used antibiotics.
Colistin Sulfomethate works by disrupting the integrity of the bacterial cell membrane, leading to leakage of intracellular components and ultimately cell death. This mechanism makes it effective against a variety of Gram-negative pathogens, including Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter baumannii, and Escherichia coli.
The drug is available in various forms, including injectable solutions and creams, and is usually administered intravenously or topically depending on the type and severity of the infection. It is important to follow the prescribed dosage and duration of treatment to ensure its effectiveness and minimize the risk of resistance development.
Like any medication, Colistin Sulfomethate may have potential side effects. Common side effects include kidney toxicity, neurotoxicity, and allergic reactions. Therefore, it is essential to monitor renal function and adjust the dosage in patients with impaired kidney function. It is also important to note that colistin, the active ingredient of Colistin Sulfomethate, is not well absorbed through the gastrointestinal tract, hence it is typically not used orally.
Overall, Colistin Sulfomethate is a potent antibiotic that is reserved for serious bacterial infections caused by multidrug-resistant Gram-negative bacteria, when other treatment options have failed or are not available.
Common Misspellings for COLISTIN SULFOMETHATE
- xolistin sulfomethate
- volistin sulfomethate
- folistin sulfomethate
- dolistin sulfomethate
- cilistin sulfomethate
- cklistin sulfomethate
- cllistin sulfomethate
- cplistin sulfomethate
- c0listin sulfomethate
- c9listin sulfomethate
- cokistin sulfomethate
- copistin sulfomethate
- cooistin sulfomethate
- colustin sulfomethate
- coljstin sulfomethate
- colkstin sulfomethate
- colostin sulfomethate
- col9stin sulfomethate
- col8stin sulfomethate
- coliatin sulfomethate
Etymology of COLISTIN SULFOMETHATE
The word "Colistin" is derived from "colistimethate", which is an antibiotic drug. "Colistimethate" itself is a combination of two words: "colistin" and "methate". The word "colistin" comes from the Latin word "colistinus", which means "residing in the colon". This name was given to the antibiotic due to its activity against certain bacteria that reside in the colon.
"Sulfomethate" is a combination of two parts: "sulfo-" and "-methate". The prefix "sulfo-" originates from "sulfur", which refers to the chemical element with the symbol "S" on the periodic table. "-Methate" is likely an abbreviation of "methylphenylmethane". "Methate" is a common suffix used for various compounds, especially drugs.
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