ETHOXYCOUMARIN O DEETHYLASE Meaning and
Definition
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Ethoxycoumarin O Deethylase is an enzyme commonly known as EROD, which plays a crucial role in the metabolism and detoxification of various compounds in living organisms, particularly in vertebrates. This enzyme is primarily found in the liver and is responsible for catalyzing the conversion of ethoxycoumarin molecules into their deethylated form.
The process of deethylation carried out by Ethoxycoumarin O Deethylase involves the removal of an ethyl group from the ethoxycoumarin substrate, resulting in the formation of a hydroxylated product. This reaction is an essential step in the metabolism of various drugs, xenobiotics, and environmental pollutants that contain an ethyl moiety. By catalyzing this transformation, EROD aids in the breakdown and elimination of potentially harmful substances from the body.
Ethoxycoumarin O Deethylase activity is often used as a biomarker to assess the induction or inhibition of drug-metabolizing enzymes within an organism. Its measurement can provide valuable information about the rate of drug metabolism, drug-drug interactions, and the susceptibility to the toxic effects of chemicals. Researchers and toxicologists commonly utilize EROD assays to evaluate the impact of environmental contaminants on the detoxification processes in organisms, as well as to understand the pharmacokinetics of drug compounds.
In summary, Ethoxycoumarin O Deethylase is an enzyme responsible for the deethylation of ethoxycoumarin compounds, facilitating the metabolism and elimination of drugs and environmental pollutants. This enzyme's activity is often studied as an important indicator of drug metabolism rates and the potential toxicological effects of various agents.
Common Misspellings for ETHOXYCOUMARIN O DEETHYLASE
- wthoxycoumarin o deethylase
- sthoxycoumarin o deethylase
- dthoxycoumarin o deethylase
- rthoxycoumarin o deethylase
- 4thoxycoumarin o deethylase
- 3thoxycoumarin o deethylase
- erhoxycoumarin o deethylase
- efhoxycoumarin o deethylase
- eghoxycoumarin o deethylase
- eyhoxycoumarin o deethylase
- e6hoxycoumarin o deethylase
- e5hoxycoumarin o deethylase
- etgoxycoumarin o deethylase
- etboxycoumarin o deethylase
- etnoxycoumarin o deethylase
- etjoxycoumarin o deethylase
- etuoxycoumarin o deethylase
- etyoxycoumarin o deethylase
- ethixycoumarin o deethylase
- ethkxycoumarin o deethylase
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