GASTRIN Meaning and
Definition
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Gastrin is a hormone that plays a crucial role in the regulation of digestive processes in the human body. It is primarily produced and secreted by specialized cells called G cells in the stomach lining, specifically located within the antrum, which is the lower part of the stomach. Gastrin acts as a stimulant for the production of gastric acid, which aids in the breakdown and digestion of food.
The secretion of gastrin is triggered by various stimuli, including the presence of food in the stomach, stomach distension, and the release of certain chemicals and neurotransmitters. Once gastrin is released into the bloodstream, it travels back to the stomach where it binds to receptors on the surface of parietal cells, stimulating them to secrete hydrochloric acid.
In addition to its role in gastric acid secretion, gastrin also has various other functions. It helps in the contraction of the smooth muscles of the stomach, which facilitates the movement of food through the digestive tract. Furthermore, gastrin promotes the growth and development of the gastric mucosa, the protective lining of the stomach.
Abnormal levels of gastrin can lead to digestive disorders such as excessive acid production, peptic ulcers, and gastroesophageal reflux disease. Gastrin receptor antagonists are medications that work by blocking the binding of gastrin to its receptors and are commonly used in the treatment of gastric acid-related conditions.
Common Misspellings for GASTRIN
Etymology of GASTRIN
The word "gastrin" is derived from the combination of two Greek words: "gaster" meaning "stomach" and the suffix "-in" which generally indicates a hormonal or proteinaceous substance. Therefore, "gastrin" refers to a hormone produced in the stomach.
Similar spelling words for GASTRIN
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