METHYLNALOXONE Meaning and
Definition
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Methylnaloxone is a chemical compound that falls under the category of opioid receptor antagonists. It is a derivative of naloxone, which is a medication commonly used to reverse the effects of opioid overdose. Methylnaloxone acts primarily by blocking the opioid receptors in the brain, thereby inhibiting the binding of opioid drugs and reducing their effects.
As a specific substance, Methylnaloxone is known for its ability to selectively target peripheral opioid receptors, primarily found in the gastrointestinal tract. By primarily acting on these receptors, Methylnaloxone can effectively counteract opioid-induced constipation, which is a common side effect experienced by individuals who use opioids for pain management purposes.
The compound is chemically modified by adding a methyl group to naloxone, hence the name "Methylnaloxone." This modification enhances its binding affinity for peripheral opioid receptors, resulting in a stronger and more specific action at these sites. In comparison to naloxone, Methylnaloxone exhibits increased oral bioavailability, making it suitable for oral administration.
Methylnaloxone is used in various pharmaceutical formulations that aim to manage opioid-induced constipation. It is often combined with an opioid agonist, such as oxycodone, in a fixed-dose combination medication. This helps to provide relief from pain while simultaneously reducing or preventing constipation.
Common Misspellings for METHYLNALOXONE
- nethylnaloxone
- kethylnaloxone
- jethylnaloxone
- mwthylnaloxone
- msthylnaloxone
- mdthylnaloxone
- mrthylnaloxone
- m4thylnaloxone
- m3thylnaloxone
- merhylnaloxone
- mefhylnaloxone
- meghylnaloxone
- meyhylnaloxone
- me6hylnaloxone
- me5hylnaloxone
- metgylnaloxone
- metbylnaloxone
- metnylnaloxone
- metjylnaloxone
- metuylnaloxone
Etymology of METHYLNALOXONE
The word "Methylnaloxone" is derived from the combination of two components: "Methyl" and "Naloxone".
1. Methyl: "Methyl" refers to the methyl group, which is a chemical functional group consisting of one carbon atom bonded to three hydrogen atoms (CH3-). It is commonly used as a prefix in organic chemistry to indicate the presence of this group.
2. Naloxone: "Naloxone" is a medication primarily used to counteract the effects of opioid overdose. It is an opioid receptor antagonist that works by binding to opioid receptors and reversing the effects of opioid drugs. Naloxone is typically administered to individuals who are experiencing an opioid overdose to quickly restore normal respiration and prevent potentially fatal consequences.
