BRCA PROTEIN Meaning and
Definition
-
BRCA (Breast Cancer) protein refers to a group of proteins involved in maintaining the stability and function of the DNA within cells. Specifically, it refers to the proteins encoded by the BRCA1 and BRCA2 genes. These genes are tumor suppressor genes, meaning they normally suppress the formation and progression of cancerous cells. Mutations or abnormalities in these genes can significantly increase the risk of certain cancers, particularly breast and ovarian cancers.
The BRCA proteins play a pivotal role in DNA repair mechanisms, specifically the repair of double-strand breaks. They act as key players in a complex network of cellular processes that help prevent the accumulation of DNA damage and the subsequent development of cancer. By repairing DNA damage, the BRCA proteins ensure the genome's integrity and stability, safeguarding against the development of abnormal cells that could lead to tumor formation.
When functioning correctly, the BRCA proteins interact with other proteins to form protective DNA repair complexes. These complexes identify errors or damage in the DNA and initiate repair processes. However, mutations in the BRCA1 or BRCA2 genes can disrupt this normal functioning, impairing the repair mechanisms and increasing the risk of DNA errors remaining uncorrected. Consequently, these errors can accumulate over time, potentially leading to the development of cancerous cells.
Due to their crucial role in genetic stability and cancer prevention, BRCA proteins have become the focus of thorough research and clinical investigations. Understanding the structure and function of these proteins can aid in the development of targeted treatments and preventive strategies for individuals with BRCA gene mutations, offering potential avenues for personalized cancer management.
Common Misspellings for BRCA PROTEIN
- vrca protein
- nrca protein
- hrca protein
- grca protein
- beca protein
- bdca protein
- bfca protein
- btca protein
- b5ca protein
- b4ca protein
- brxa protein
- brva protein
- brfa protein
- brda protein
- brcz protein
- brcs protein
- brcw protein
- brcq protein
- brca orotein
- brca lrotein
Etymology of BRCA PROTEIN
The term "BRCA protein" is derived from the acronym BRCA, which stands for "Breast Cancer Susceptibility Gene". The gene was discovered in the mid-1990s and named BRCA1 and BRCA2, indicating the first and second genes identified in relation to breast cancer susceptibility. These genes are responsible for producing proteins that help suppress tumor growth and maintain the stability of the cell's DNA. Therefore, the term "BRCA protein" refers to the protein products encoded by the BRCA1 and BRCA2 genes.
Infographic
Add the infographic to your website:
